Curcumin Induces Nrf2 Nuclear Translocation and Prevents Glomerular Hypertension, Hyperfiltration, Oxidant Stress, and the Decrease in Antioxidant Enzymes in 5/6 Nephrectomized Rats

Figure 1

Curcumin (60 mg/kg/day) ameliorated 5/6NX-induced increase in (a) blood urea nitrogen (BUN), (b) plasma creatinine, (c) proteinuria, and (d) systolic blood pressure. BUN and plasma creatinine were measured at the end of the study (day 30). Data are mean ± SEM of 8–10 rats. *𝑃<0.05 versus control, **𝑃<0.05 versus 5/6NX.

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