Oxidative Stress Markers in Prostate Cancer Patients after HDR Brachytherapy Combined with External Beam Radiation

Table 2

Markers of oxidative stress in blood of prostate cancer patients and in control group.

	Control	Patients
		Before therapy	After radiotherapy
			Immediately	1.5–3 months	2 years
SOD (U/g Hb)	1017.9±253.5	1292.7±534.6	1377.1±646.1	1237.7±542.1	789.9±113.3
CAT (10^4 IU/g Hb)	58.62±10.04	62.48±13.79	63.31±16.19	61.16±14.2	58.1±11.4
GPx (U/g Hb)	12.2±6.3	8.1** ± 3.9	6.1** ± 3.1	8.5^*a ± 4.2	4.8** ± 1.9
TBARSeryth. (nmol MDA/g Hb)	24.1±8.8	43.0** ± 19.7	38.5* ± 19.7	41.0** ± 16.3	29.8±11.4
TBARSplasma (10^−2 nmol MDA/mL)	28.5±8.8	44.6** ± 19.7	45.7** ± 19.7	43.2** ± 16.3	46.4* ± 15.6

SOD: superoxide dismutase; CAT: catalase; GPx: glutathione peroxidase; TBARSs: thiobarbituric acid reactive substances.
Data expressed as mean 𝑥±SD; *𝑃<0.05; **𝑃<0.001 compared with control group.
^a𝑃<0.05 immediately after radiotherapy.