Comparative Effects of Biodynes, Tocotrienol-Rich Fraction, and Tocopherol in Enhancing Collagen Synthesis and Inhibiting Collagen Degradation in Stress-Induced Premature Senescence Model of Human Diploid Fibroblasts
Figure 1
Effects of biodynes, TRF, and tocopherol on COL1A1 gene and procollagen type I protein expression in HDFs. COL1A1 expression (a). Biodynes, TRF, tocopherol, and BTT significantly increased COL1A1 expression compared to SIPS. Procollagen type I protein expression (b). TRF, tocopherol, and BTT significantly increased the expression of procollagen type I. aDenotes compared to SIPS, bdenotes compared to biodynes, cdenotes compared to TRF, and ddenotes compared to tocopherol. Data are presented as the mean of three experiments ±S.D, .