Function and Characteristics of PINK1 in Mitochondria

Figure 1

Implication of mitochondrial dysfunction caused by PINK1, Parkin, and so on for neurodegenerative disorders including Parkinson’s disease. Abnormality of these molecules may also be a causative factor in the development of mitochondrial dysfunction. There is a relationship between mitochondrial dysfunction and neurodegenerative disorders. Note that some critical molecules have been omitted for clarity.