Sulforaphane Attenuation of Type 2 Diabetes-Induced Aortic Damage Was Associated with the Upregulation of Nrf2 Expression and Function

Figure 8

Effects of SFN on aortic expression of Nrf2 downstream genes. Aortic expression of Nrf2 downstream genes SOD-1 expression was examined by immunohistochemical staining for protein expression (a) in aortic tunica media with semiquantitative analysis (b) and real-time PCR at mRNA level SOD-1 (c) and HO-1 (d). Data were presented as means ± SD (𝑛=6). ^∗𝑃<0.05 versus corresponding Ctrl; ^#𝑃<0.05 versus corresponding DM. Bar = 50 μM.

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