Research Article

Plasma Levels of Aminothiols, Nitrite, Nitrate, and Malondialdehyde in Myelodysplastic Syndromes in the Context of Clinical Outcomes and as a Consequence of Iron Overload

Table 3

Overview of the analyzed study groups (0–4), the number of myelodysplastic patients, gender ratio, and the age of analyzed patients and controls.

GroupNumber of patients (male/female)Age rangeDiagnoses

023 (10/13)25–57Healthy donors
114 (10/4)52–91RA, RA-5q, RARS
229 (15/14)28–90RCMD, RCMD-RS, RCMD-5q, RCMD with reactive monocytes
39 (4/5)36–85RAEB-1, MDS/MPS, MDS/MPS with 5q deletion, MDS-RAEB-1 + SC-NHL
49 (5/4)55–80RAEB-2, RAEB-T, AML M2

Refractory anemia (RA), MDS with isolated del(5q) (RA-5q), refractory anemia with ringed sideroblasts (RARS), refractory cytopenia with multilineage dysplasia (RCMD), RCMD with ringed sideroblasts (RCMD-RS), RCMD with 5q deletion (RCMD-5q), RCMD with reactive monocytes, RA with an excess of blasts-1 (RAEB-1), RA with an excess of blasts-2 (RAEB-2), RA with an excess of blasts in transformation (RAEB-T), myelodysplastic/myeloproliferative syndromes (MDS/MPS), MDS/MPS with 5q deletion, acute myeloid leukemia (AML M2), and MDS-RAEB-1 plus SC-non-Hodgkin lymphoma.