Aging Leads to Elevation of O-GlcNAcylation and Disruption of Mitochondrial Homeostasis in Retina

Figure 4

Alterations of MAPK pathway in retinas of young and old rats. SD rats aged five months (young) and 25 months (old) were sacrificed; total proteins of retina tissues were prepared for analysis. MAPK pathway activation statuses were analyzed by Western blot ((a) Western blot image, (b) statistical analysis of p-Erk1/2, (c) statistical analysis of p-JNK, and (d) statistical analysis of p-p38). The values are the means ± S.E.M from 8 rats per group. ^∗𝑃<0.05 and ^∗∗𝑃<0.01 as calculated by Student’s 𝑡-test.

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