Dietary Blueberry and Bifidobacteria Attenuate Nonalcoholic Fatty Liver Disease in Rats by Affecting SIRT1-Mediated Signaling Pathway

Figure 1

The flowchart of study. HFD: high-fat diet; NAFLD: nonalcoholic fatty liver disease; CG: a group with normal rats was assigned as a control group; MG: NAFLD model group; SI: SIRT1 RNAi group; BJ: blueberry juice group; BJSI: blueberry juice + SIRT1 RNAi group; BJB: blueberry juice + bifidobacteria group; BJBSI: blueberry juice + bifidobacteria + SIRT1 RNAi group; SOD: superoxide dismutase; GSH: reduced glutathione; AST: aspartate aminotransferase; ALT: alanine aminotransferase; TG: total triglyceride; TC: total cholesterol; HDL-c: high-density lipoprotein-cholesterol; LDL-c: low-density lipoprotein-cholesterol; MDA: malondialdehyde.