Nitric Oxide Synthetic Pathway in Patients with Microvascular Angina and Its Relations with Oxidative Stress

Figure 3

NO synthase and arginase expression in human RBCs. Representative immunofluorescent images (630x magnification) of RBCs isolated from patients with microvascular angina (MVA) or coronary artery disease (CAD) or healthy subjects (Ctrl), stained for RBC-NOS (a) or arginase I (b). Data are expressed as the mean of fluorescent intensity ± SD subtracted of the negative control value (at least three fields were analyzed, 𝑛=10 subjects for each group). ^∗𝑃<0.05 versus CAD; ^#𝑃<0.05, ^###𝑃<0.001 versus Ctrl.

(a)

(b)