Aronia melanocarpa Elliot Reduces the Activity of Angiotensin I-Converting Enzyme—In Vitro and Ex Vivo Studies

Table 1

Characteristics of control group and patients with metabolic syndrome (mean ± SD) at baseline and after 1 (1 M) and 2 months (2 M) of Aronia melanocarpa Elliot extract supplementation: TC-total cholesterol, LDL-low-density lipoprotein cholesterol, HDL-high-density lipoprotein cholesterol, TG-triglyceride, BMI-body mass index, SBP-systolic blood pressure, DBP-diastolic blood pressure, CRP-C-reactive protein, NE-not evaluated, and NS-not statistically significant.

Parameters	Patients with MS; (group I)			Control; (group II); (𝑛=20)	Control group MS; (group III); (𝑛=25)
	At baseline; (𝑛=23)	After 1 M; (𝑛=23)	After 2 M; (𝑛=23)
TC; (mg/dL)	237.6±36.9^𝑃=0.002	220.5±32^NS/∗∗	216.7±33.7^NS/∗∗	206.6±32.3	224.4±45.2^NS
LDL; (mg/dL)	151.7±36.1^𝑃<0.001	142.7±33.3^𝑃=0.008/∗∗	139.2±30.9^𝑃=0.013/∗∗	122.9±28.7	135.6±40.1^NS
HDL; (mg/dL)	49.9±11.5^𝑃=0.002	51.5±13.7^𝑃=0.008	44.1±12.1^𝑃=0.003	64.8±16.7	59.2±19.9^NS
BMI; (kg/m^2)	30.9±3.7^𝑃=0.002	30.0±3.5^𝑃=0.001	30.4±3.7^𝑃<0.001	23.0±1.5	29.2±2.8^𝑃=0.005
Waist circumference; (cm)	95.0±9.4^𝑃<0.001	93.4±8.8^𝑃=0.002	93.7±8.5^𝑃=0.001	84.6±8.5	97.2±8.8^𝑃<0.001
SBP; mmHg	136.8±10.9^𝑃<0.001	130.0±9.0^𝑃=0.005/∗∗	126.3±11.6^𝑃=0.014/∗∗	121.3±10.2	149.0±20.4^𝑃=0.02
DBP; mmHg	86.8±16.0^𝑃=0.002	83.1±8.2^𝑃<0.001	80.5±7.9^𝑃=0.005	73.5±7.3	84.0±7.6^𝑃<0.001
CRP; mg/dL	3.1±2.3	2.9±2.6^NS	2.5±1.7^NS	NE	NE

^∗∗𝑃<0.05 versus baseline; 𝑃 = values versus control healthy group (group II).