Research Article
In Vitro Antioxidant and Cytotoxic Activities of Arnebia benthamii (Wall ex. G. Don): A Critically Endangered Medicinal Plant of Kashmir Valley
Table 2
Cytotoxicity of the different crude extracts of Arnebia benthamii and 5-fluorouracil (5-FU) and Paclitaxel on six human cancer cell lines.
| | Cell line type | HOP-62 | A549 | PC-3 | THP-1 | HCT-116 | MIA-Pa-Ca | | Tissue type | Lung | Lung | Prostate | Leukemia | Colon | Pancreatic | | S. no. | Code | Conc. (g/mL) | %Age growth inhibition |
| | 1 | EB-MET | 100 | 100 | 100 | 0 | 90 | 63 | 100 | | 2 | EB-MET | 50 | 46 | 13 | 0 | 45 | 49 | 47 | | 3 | EB-MET | 10 | 33 | 18 | 0 | 48 | 40 | 25 | | 4 | EB-ETH | 100 | 55 | 42 | 0 | 65 | 57 | 55 | | 5 | EB-ETH | 50 | 49 | 24 | 0 | 62 | 57 | 44 | | 6 | EB-ETH | 10 | 43 | 0 | 0 | 57 | 47 | 40 | | 7 | EB-EA | 100 | 39 | 21 | 35 | 68 | 72 | 66 | | 8 | EB-EA | 50 | 24 | 0 | 6 | 7 | 8 | 23 | | 9 | EB-EA | 10 | 0 | 0 | 0 | 0 | 0 | 0 | | 10 | EB-PE | 100 | 47 | 54 | 39 | 29 | 19 | 0 | | 11 | EB-PE | 50 | 47 | 53 | 10 | 18 | 14 | 0 | | 12 | EB-PE | 10 | 39 | 15 | 0 | 1 | 12 | 0 | | 13 | EB-AQ | 100 | 35 | 36 | 0 | 56 | 44 | 40 | | 14 | EB-AQ | 50 | 32 | 24 | 0 | 28 | 42 | 30 | | 15 | EB-AQ | 10 | 24 | 17 | 0 | 9 | 10 | 12 | | 16 | 5-FU | 20 M | — | — | — | 67 | 67 | — | | 17 | Paclitaxel | 1 M | 72 | 70 | — | | — | — |
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Data are means ± SD of three independent experiments.
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