Research Article

High Potency of a Novel Resveratrol Derivative, 3,3′,4,4′-Tetrahydroxy-trans-stilbene, against Ovarian Cancer Is Associated with an Oxidative Stress-Mediated Imbalance between DNA Damage Accumulation and Repair

Table 1

Half-maximal inhibitory concentrations (IC50) estimated for RVT and 3,3′,4,4′-THS according to the results of MTT and LDH release assays.

MTT assayLDH release assay
RVT3,3′,4,4′-THSRVT3,3′,4,4′-THS

A278048 μM4 μM65 μM6 μM
OVCAR-3480 μM50 μM525 μM85 μM
SKOV-3380 μM8 μM346 μM10 μM
HOSE cells485 μM502 μM421 μM532 μM
HPMCs465 μM496 μM495 μM498 μM