Nitric Oxide Regulates Neurogenesis in the Hippocampus following Seizures

Figure 1

Experimental protocol for assessment of NSC proliferation (a) and differentiation (b and c). (a) KA or saline solutions were subcutaneously injected (25 mg/kg). Intraperitoneal injections (i.p.) of BrdU (4 doses, 50 mg/kg) were administrated every 2 hours, up to 12 hours before transcardiac perfusion (P). (b) Administration protocol of BrdU 3 days after SE. (c) Administration protocol of BrdU 7 days after SE. Intraperitoneal injections (i.p.) of BrdU (4 doses, 50 mg/kg) were administrated every 12 hours. Perfusions (P) were performed 3 weeks after BrdU treatment, following anesthesia.

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