Nitric Oxide Regulates Neurogenesis in the Hippocampus following Seizures

Figure 5

The number of BrdU+ cells in the dentate gyrus born 7 days after SE is not affected by NO, 21 days after treatment with BrdU. (a) Representative images of BrdU (green) and NeuN (red) positive cells in the dentate gyrus, 7 days after treatment with KA or saline in iNOS^+/+ and iNOS^−/− mice. Scale bar: 20 μm. (b) Number of BrdU+ cells in iNOS^+/+ and iNOS^−/− mice. Data are expressed as means ± SEM. Two-factor ANOVA (Bonferroni’s posttest), to 6, . (c) BrdU+ cells in the three regions of the dentate gyrus. Data are expressed as means ± SEM. Two-factor ANOVA (Bonferroni’s posttest), to 6, .

(a)

(b)

(c)