3-(3-Pyridylmethylidene)-2-indolinone Reduces the Severity of Colonic Injury in a Murine Model of Experimental Colitis

Figure 2

PMID pretreatment attenuated the levels of proinflammatory markers in serum of DSS-induced ICR mice. Following treatment with the indicated doses of PMID per os for 7 days, colitis was induced by DSS (3%) via drinking water for 7 days. Then the serum was collected and the protein levels of TNFα, IL-6, IFN-γ, and MCP-1 were analyzed using CBA just as “Section 2” described. Results represented mean ± SD. /group. The statistical difference between the samples was demonstrated as or .

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