Research Article

The Effects of Age and Latent Cytomegalovirus Infection on NK-Cell Phenotype and Exercise Responsiveness in Man

Table 1

Physical characteristics of the participants ( = 20; = 20). Data are mean ± SD. CMV seronegative and CMV seropositive participants indicated by − and +, respectively. Statistical differences between younger (23–39 yrs) and older (50–64 yrs) subjects are indicated by # < 0.05. CMV serostatus did not affect any of the physical characteristics ( > 0.05).

CharacteristicsYounger (−)
[ = 12]
Younger (+)
[ = 12]
Older (−)
[ = 8]
Older (+)
[ = 8]
One-way ANOVA
statistic ( value)
CMVAge

Age (years) 30.8 ± 6.430.0 ± 6.055.6 ± 3.6#57.1 ± 4.1#<0.1 (0.88)163.1 (<0.001)
Height (cm)179.4 ± 7.1177.9 ± 5.4178.2 ± 8.6177.2 ± 6.31.3 (0.26)0.1 (0.72)
Mass (kg)81.2 ± 12.882.8 ± 12.179.6 ± 8.179.8 ± 10.2<0.1 (0.98)<0.1 (0.84)
BMI (kg⋅m−2) 25.1 ± 3.225.7 ± 4.724.8 ± 2.125.8 ± 2.70.5 (0.45)<0.1 (0.90)
Maximum power (W)241.3 ± 76.5226.2 ± 57.0235.7 ± 65.6225.8 ± 38.80.4 (0.53)<0.1 (0.88)
O2max (mL⋅kg−1⋅min−1) 39.6 ± 13.036.7 ± 6.340.7 ± 17.440.3 ± 7.50.4 (0.49)<0.1 (0.90)
Maximum heart rate (bpm)187.7 ± 6.1187.8 ± 5.8164.4 ± 3.6164.9 ± 3.7<0.1 (0.87)163.4 (<0.001)
Physical activity ratinga (0–7)5.0 ± 2.25.4 ± 2.16.3 ± 1.05.6 ± 1.9<0.1 (0.90)3.2 (0.09)
Age-adjusted fitness scoreb (1–5)3.6 ± 1.83.1 ± 1.14.1 ± 1.23.7 ± 1.0<0.1 (0.83)2.2 (0.14)

Exercise measures
Mean power (W)183.6 ± 63.5175.8 ± 61.1181.3 ± 38.5172.4 ± 29.70.2 (0.62)<0.1 (0.87)
Mean power (% max)76.3 ± 11.977.5 ± 13.877.9 ± 6.276.7 ± 7.0<0.1 (0.99)<0.1 (0.92)
Mean Heart rate (bpm)158.7 ± 10.3159.6 ± 7.5151.0 ± 7.8#147.5 ± 8.1#0.2 (0.64)13.1 (0.001)
Mean heart rate (% max)85.4 ± 5.484.5 ± 2.791.7 ± 4.9#89.1 ± 3.7#1.8 (0.20)14.6 (<0.001)

Maximum heart rate estimated by the equation: 191.5 − (0.007 × age2) [27].
aPhysical Activity Rating (PA-R) calculated from Jackson Questionnaire [28].
bAge-adjusted Fitness Score calculated from Adams and Beam equations [29].