Modulation of Hydrogen Peroxide-Induced Oxidative Stress in Human Neuronal Cells by Thymoquinone-Rich Fraction and Thymoquinone via Transcriptomic Regulation of Antioxidant and Apoptotic Signaling Genes

Figure 4

Phase-contrast micrograph observation on SH-SY5Y at 40x magnification. (a) Untreated cells (control), (b) 250 μM H₂O₂ alone, (c) 0.03 μg/mL TQRF + 250 μM H₂O₂, (d) 0.1 μg/mL TQRF + 250 μM H₂O₂, (e) 0.03 μg/mL TQ + 250 μM H₂O₂, and (f) 0.1 μg/mL TQ + 250 μM H₂O₂.

(a) Control

(b) 250 μM H₂O₂

(c) 0.03 μg/mL TQRF + 250 μM

(d) 0.1 μg/mL TQRF + 250 μM

(e) 0.03 μg/mL TQ + 250 μM H₂O₂

(f) 0.1 μg/mL TQ + 250 μM H₂O₂