Modulation of Tamoxifen Cytotoxicity by Caffeic Acid Phenethyl Ester in MCF-7 Breast Cancer Cells

Figure 4

Caspase-3 activity in MCF-7 cells. Caspase-3 activity after 24 h (a) and 48 h (b) treatments with (10 μM), CAPE (4 μM), and their combination. Results were expressed as means ± SD of 3 independent experiments performed in triplets. value < 0.05 is considered significant. A: significantly different from the respective concentration of control at . B: significantly different from the respective concentration of TAM at . C: significant difference of 48 h treatment from the respective concentration at 24 h at .

(a)

(b)