Protective Effect of Peroxisome Proliferator-Activated Receptor α Activation against Cardiac Ischemia-Reperfusion Injury Is Related to Upregulation of Uncoupling Protein-3

Table 1

Hemodynamic data during ischemia-reperfusion.

	MAP (mmHg)		Heart rate (beats/min)		RPP (mmHg⋅beats/min)
	Control	WY	Control	WY	Control	WY
Baseline	94 ± 15	107 ± 11	440 ± 40	450 ± 29	41438 ± 8847	48432 ± 6877
Before ischemia	97 ± 13	94 ± 24	435 ± 43	452 ± 42	42506 ± 7402	42428 ± 10754
Before reperfusion	89 ± 23	82 ± 24	436 ± 62	441 ± 76	39042 ± 12347	36719 ± 15041
15 min after reperfusion	77 ± 19	91 ± 27	401 ± 56	426 ± 57	31403 ± 11025	39381 ± 13750
30 min after reperfusion	77 ± 15	88 ± 15	419 ± 60	418 ± 62	32688 ± 9924	37592 ± 10024
60 min after reperfusion	75 ± 26	91 ± 15	419 ± 53	418 ± 60	32117 ± 13794	38494 ± 8261
2 h after reperfusion	87 ± 17	91 ± 22	425 ± 59	405 ± 43	37259 ± 9170	37268 ± 9514

Data are expressed as mean ± SD. versus baseline.
MAP: mean arterial pressure; RPP: rate pressure product; WY: WY-14643 group.