Central Infusion of Angiotensin II Type 2 Receptor Agonist Compound 21 Attenuates DOCA/NaCl-Induced Hypertension in Female Rats

Figure 5

mRNA levels for renin-angiotensin system components (AT1-R and AT2-R (a); ACE1 and ACE2 (b)) and inflammatory cytokines (TNF-α and IL-10 (c)) in the PVN in each group of females with or without central infusion of C21 during DOCA/NaCl treatment. Values are mean ± SEM and expressed as a fold change relative to corresponding control (intact females). per group; compared to control intact females; compared to intact and OVX females with central vehicle plus systemic DOCA/NaCl. compared to intact females with central vehicle plus systemic DOCA/NaCl.

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