GST-TAT-SOD: Cell Permeable Bifunctional Antioxidant Enzyme—A Potential Selective Radioprotector

Figure 6

Annexin-V/PI analysis of apoptosis in L-02 (a) and Hep G2 (b) cells at 24 h after treatment with 4 Gy of irradiation. Cells were stained with Annexin-V FITC and PI and detected by flow cytometry. The lower right quadrant (Annexin-V⁺ PI⁻) represents early apoptosis, whereas upper right quadrant (Annexin-V⁺ PI⁺) represents late apoptosis ((A) CON; (B) XRT; (C) XRT+SOD; (D) XRT+AMFT; (E) XRT+GST-TAT-SOD; (F) XRT+SOD-TAT). (c) Total apoptotic index of cells with different treatment.

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(b)

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