A Mechanistic Study on the Amiodarone-Induced Pulmonary Toxicity

Figure 17

Effect of amiodarone on rat lung histopathology. Amiodarone was given (80 mg/kg/day i.p.) for three weeks. Microscopic description: inflamed lung tissue showing nodular collection of lymphocytes and subpleural granulomas with multinucleated giant cells. The lung tissue is emphysematous and congested. Histopathologic diagnosis: granulomatous inflammation.