Salvianolic Acid B Prevents Iodinated Contrast Media-Induced Acute Renal Injury in Rats via the PI3K/Akt/Nrf2 Pathway

Figure 1

Protective effects of SB against CI-AKI. SB (50 mg/kg) ameliorated CM-induced increase in (a) the Scr level, (b) the BUN level, and (c) histologic injury scoring at 24 h after the intravenous injection of 10 mL/kg iohexol (350). (d) Representative histological image of kidney from representative photomicrographs of tubular cell injury in rat kidney tissue sections. SB significantly attenuated the renal tubular injury at 24 h after the injection of iohexol. Original magnification: ×200. HE staining. versus the CM group; . The values shown are the mean ± SD.

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