MnTBAP Therapy Attenuates Renal Fibrosis in Mice with 5/6 Nephrectomy

<div>TGF-<i>β</i>1 induced mitochondrial dysfunction in mPTCs. (a) Analysis of mitochondrial membrane potential by JC-1 fluorescence dye in mPTCs treated with TGF-<i>β</i>1. (b) qRT-PCR analysis of mtDNA copy number in mPTCs treated with TGF-<i>β</i>1. (c) Analysis of ROS by DCF fluorescence in mPTCs treated with TGF-<i>β</i>1. (d) Electron microscopy analysis of mitochondrial morphology. 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Oxidative Medicine and Cellular Longevity

fig2

Figure 2

Figure 2: MnTBAP Therapy Attenuates Renal Fibrosis in Mice with 5/6 Nephrectomy 