Oxidative Stress Biomarkers and Left Ventricular Hypertrophy in Children with Chronic Kidney Disease
Table 1
Basic clinical data and kidney function parameters depending on CKD stage in the investigated group of 65 patients.
Parameter
CKD stage
value
1 + 2 ()
3 ()
4 ()
5 ()
Age (years)
10.51 (5.04; 16.08)
11.33 (5.15; 16.33)
12.01 (8.70; 15.99)
11.61 (8.51; 15.20)
0.820
Height (-score)
0.078 (−0.300; 0.569)
−0.716 (−2.303; 0.060)
−0.868 (−1.484; −0.210)
−1.495 (−3.444; −0.130)
0.013
Body mass (-score)
−0.015 (−0.409; 0.419)
−0.980 (−1.635; 0.009)
−0.464 (−1.054; 0.228)
−1.587 (−3.714; −0.828)
0.002
BMI (kg/m2)
16.5 (15.8; 22.1)
16.6 (14.7; 19.5)
18.1 (16.0; 20.4)
15.9 (14.5; 17.2)
0.224
BMI (-score)
0.316 (−0.318; 0.712)
−0.779 (−1.636; 0.433)
0.079 (−0.638; 0.712)
−1.252 (−1.599; −0.621)
0.020
Creatinine (µmol/L)
69.3 (34.0; 93.8)
113.8 (95.0; 146.4)
274.9 (203.8; 311.9)
501.8 (414.3; 869.0)
<0.001
Cystatin C (mg/L)
0.86 (0.68; 1.23)
1.45 (1.17; 1.86)
2.6 (2.23; 3.01)
4.81 (4.14; 6.53)
<0.001
eGFR Filler(mL/min/1.73 m2)
109.46 (72.62; 141.28)
60.13 (45.64; 76.81)
29.49 (26.19; 36.49)
14.77 (9.78; 18.43)
<0.001
Values presented as median (25th–75th percentile). BMI—body mass index; eGFR—estimated glomerular filtration rate. Statistically significant differences between stages 1 + 2 and 4, 1 + 2 and 5. Statistically significant differences between stages 1 + 2 and 3, 1 + 2 and 5, 4 and 5. Statistically significant differences between stages 4 and 5. Statistically significant differences between all stages.
