Liver Damage in Patients with HCV/HIV Coinfection Is Linked to HIV-Related Oxidative Stress

Figure 3

Serum GSSG concentrations are higher in HIV-infected patients with abnormal than in those with normal ALT/AST. Mean ± standard error of the mean (SEM) serum GSSG concentrations in HIV-negative chronic HCV carriers, HIV-positive chronic HCV carriers, HIV-negative HCV resolvers, HIV-positive HCV resolvers, and healthy controls with normal (≤40 IU/L) and abnormal (>40 IU/L) serum ALT (left panel) or AST (right panel). Unpaired nonparametric -tests were used for between-group comparisons. Average and SEM were indicated for each group. All values were two-tailed, with considered statistically significant.

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