Lycium barbarum Polysaccharides Protect against Trimethyltin Chloride-Induced Apoptosis via Sonic Hedgehog and PI3K/Akt Signaling Pathways in Mouse Neuro-2a Cells

Figure 7

Effects of antagonists on ROS, MDA generation, and SOD activity caused by TMT in N2a cells. Cells were cultured with 3.75 μM TMT, pretreated with or without different inhibitors at different time points in different concentration (LY2940002, 10 μM; GDC-0449, 30 μM), and quantified to evaluate ROS, MDA, and SOD productions. Results are expressed as mean ± SD (). , compared with the control group; , compared with the TMT-treated group.

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