Impact of Continuous Erythropoietin Receptor Activator on Selected Biomarkers of Cardiovascular Disease and Left Ventricle Structure and Function in Chronic Kidney Disease

Table 3

Correlations between serum Hb concentration and evaluated biomarkers in CKD patients.

Biomarkers	CKD patients before treatment	CKD patients after treatment
	Hb	Hb
	IL-1β (pg/mL)	−0.140	0.117
sTNF-RI (pg/mL)	−0.040	−0.444
sTNF-RII (pg/mL)	−0.157	0.270
sFasL (pg/mL)	−0.307	−0.015
sFas (pg/mL)	−0.196	−0.164
sE-selectin (ng/mL)	−0.025	−0.023
sICAM-1 (ng/mL)	0.148	−0.403
TIMP-1 (ng/mL)	−0.156	−0.222
sVCAM-1 (ng/mL)	0.116	0.083
MMP-9 (ng/mL)	0.102	−0.140
TGF-β1 (pg/mL)	−0.026	−0.138

Spearman correlation coefficient values, .
Hb = hemoglobin, CKD = chronic kidney disease, IL-1β = interleukin 1β, TNF-RI = soluble tumor necrosis factor receptor I, TNF-RII = soluble tumor necrosis factor receptor II, sFasL = soluble Fas ligand, sFas = soluble Fas, sICAM-1 = soluble intercellular adhesion molecule-1, TIMP-1 = tissue inhibitor of metalloproteinase-1, sVCAM-1 = soluble human vascular cell adhesion molecule-1, MMP-9 = metalloproteinase-9, and TGF-β1 = transforming growth factor- beta 1.