A Decrease of Brain MicroRNA-122 Level Is an Early Marker of Cerebrovascular Disease in the Stroke-Prone Spontaneously Hypertensive Rat

Figure 2

Characterization of protein expression level of vWF, ICAM-1, CD31, and eNOS in the brains of JD- versus RD-fed SHRSR and SHRSP strains. Representative Western blots with corresponding densitometric analysis are shown for the four indicated proteins in the two strains (SHRSR, left side; SHRSP, right side). (a) vWF expression level; JD- versus RD-fed SHRSR; JD- versus RD-fed SHRSP. (b) ICAM-1 expression level; JD- versus RD-fed SHRSP. (c) CD31 expression level; JD- versus RD-fed SHRSP. (d) eNOS and phospho-eNOS expression level; JD- versus RD-fed SHRSR. JD = high-salt Japanese style diet; RD = regular diet. for each experimental group.

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