Redox Regulating Enzymes and Connected MicroRNA Regulators Have Prognostic Value in Classical Hodgkin Lymphomas

Table 3

Two-sided values < 0.05 when the clinicopathological parameters are set against mRNA and miRNA expression. ↑ and ↓ indicate the direction of the correlation.

Expression of mRNA or miRNA	Histology	Stage		B-symptoms	Risk factors		Disease-specific survival
		Limited	Advanced		Limited disease	Advanced disease	Limited disease	Advanced disease
PRDX I	0.008^1				0.027
miR-510
PRDX II
miR-122↑				0.037			0.015
PRDX III
miR-23b↑			0.021	0.025
miR-383↑	0.019^1		0.014	0.013	0.015
MnSOD↑				0.006				0.045
miR-212↑			0.047
Nrf2↑					0.027
miR-28↑			0.036
miR-93
miR-144
Keap1
miR-200a↑	0.044^1

Most frequently expressed in nodular sclerosis subtype followed by mixed cell histology and least expressed in lymphocyte-rich subtype.