Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell

<div>Selective cytotoxicity of Asc/TETA on various cell lines. MCF-7, MDA-MB-157, MDA-MB-231, U87, HCC-9204, H1299, Hs578Bst, HUVEC, or V79 cells were incubated with 1 mM, 3 mM, or 5 mM of Asc, respectively, along with 10 <i>μ</i>M, 30 <i>μ</i>M, or 50 <i>μ</i>M of TETA to maintain 1 : 100 TETA-to-Asc ratio. MTT assay was performed to assess the cytotoxicity of Asc/TETA on different cell lines after 12 hours of incubation; experiment was repeated three times.</div>

Oxidative Medicine and Cellular Longevity

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Figure 3: Triethylenetetramine Synergizes with Pharmacologic Ascorbic Acid in Hydrogen Peroxide Mediated Selective Toxicity to Breast Cancer Cell 