Sirt1 Protects Endothelial Cells against LPS-Induced Barrier Dysfunction

Figure 1

Effects of LPS on EC permeability. Cells were (a, b) treated with 500 ng/mL of LPS for 3, 6, 9, 12, and 24 h or with LPS (c, d) at 100, 200, and 500 ng/mL for 24 h, compared to the control with the culture medium. Permeability was assessed by TER and flux of FITC-dextran. per group. versus control.

(a)

(b)

(c)

(d)