Amifostine Pretreatment Attenuates Myocardial Ischemia/Reperfusion Injury by Inhibiting Apoptosis and Oxidative Stress

Figure 1

Amifostine pretreatment reduces myocardial I/R injury. (a) Representative images of the infract area (INF: white), area at risk (AAR: red and white), and normal area (blue). (b) Quantitative analysis of infarct size and the ratio of INF/AAR. Data are shown as means ± SEM; , I/R (pretreated with NS) control group versus Sham group; I/R + H (pretreated with amifostine 400 mg/kg) group versus I/R control group; per group.

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