Age and Environment Influences on Mouse Prion Disease Progression: Behavioral Changes and Morphometry and Stereology of Hippocampal Astrocytes

Figure 2

Burrowing activity. (a) Amount of burrowed food in the ME7-SE group compared to NBH-SE controls. Note significant reduction at 11 wai in ME7-SE compared with NBH-SE and at 15 wai in ME7-EE compared with NBH-EE. (b) ME7-SE young mice were different from ME7-A mice between 13 and 16 wai, and NBH-A showed a reduction in burrowing activity at 16 wai. (, versus NBH-SE; versus NBH-EE; versus ME7-A; versus NBH-SE; Two-way repeated measures Bonferroni posttests).

(a)

(b)