Baicalin Ameliorates Liver Injury Induced by Chronic plus Binge Ethanol Feeding by Modulating Oxidative Stress and Inflammation via CYP2E1 and NRF2 in Mice

Figure 5

Baicalin treatment reduces mRNA expression of ROS-generating enzymes in the liver tissues. Hepatic mRNA of NOX2 (a), p67phox (b), xanthine oxidase (c), and iNOS (d) were analyzed by real-time PCR. The results are expressed as fold change relative to the pair-fed group. Values represent means ± SEM and /group. versus pair-fed group, ^# versus EtOH group. (e) Microsomal CYP2E1 activities among various groups. Values represent means ± SEM and /group. versus pair-fed group, ^# versus EtOH group.

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