Comparison of Effects of Different Statins on Contrast-Induced Acute Kidney Injury in Rats: Histopathological and Biochemical Findings

Figure 1

Histopathological evaluation of kidney tissues in a rat model of CI-AKI with or without statin treatment. Representative photomicrographs show H&E-stained kidney sections (a–j) and semiquantitative analysis of tubular necrosis and medullary congestion (k, l). Control group (a, f); CI-AKI group (b, g); CI-AKI + RUS (c, h); CI-AKI + SSTN (d, i); and CI-AKI + ATO (e, j). Original magnification: ×100. Calibration bar = 200 μm. Results are expressed as mean ± SEM (). versus control group; , versus CI-AKI group. ATO: atorvastatin; CI-AKI: contrast-induced acute kidney injury; H&E: hematoxylin and eosin; RUS: rosuvastatin; SSTN: simvastatin.

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