Research Article

Effects of Chimonanthus nitens Oliv. Leaf Extract on Glycolipid Metabolism and Antioxidant Capacity in Diabetic Model Mice

Table 3

Effects of COE on OGTT in diabetic model mice.

GroupsBG (mmol/L)
0 h0.5 h1 h2 h

NC6.17 ± 0.648.13 ± 0.646.37 ± 0.326.23 ± 1.17
DM28.67 ± 0.25ΔΔ33.03 ± 0.46ΔΔ29.83 ± 0.93ΔΔ28.70 ± 2.46ΔΔ
COE-L23.10 ± 1.59ΔΔ29.93 ± 1.53ΔΔ24.73 ± 0.55ΔΔ24.17 ± 0.45ΔΔ
COE-H18.07 ± 2.10ΔΔ25.60 ± 0.40ΔΔ23.20 ± 2.05ΔΔ21.07 ± 1.65ΔΔ
ROS20.53 ± 2.91ΔΔ27.60 ± 2.04ΔΔ25.07 ± 0.95ΔΔ20.40 ± 2.14ΔΔ

Data were presented as mean ± standard deviation (). OGTT: oral glucose tolerance test; BG: blood glucose level. After three weeks of treatment, all animals were intragastric administrated with 2.0 g/kg body wt. of glucose and then their blood glucose level were measured at 0, 0.5 h, 1 h, and 2 h. and compared to group DM; ΔΔ compared to group NC.