Research Article

Effects of Chimonanthus nitens Oliv. Leaf Extract on Glycolipid Metabolism and Antioxidant Capacity in Diabetic Model Mice

Table 4

Effects of COE on serum lipid profile in diabetic model mice after 4 weeks of treatment.

GroupsTG (mmol/L)TC (mmol/L)HDLC (mmol/L)LDLC (mmol/L)

NC1.03 ± 0.381.81 ± 0.412.34 ± 0.240.20 ± 0.05
DM2.06 ± 0.43ΔΔ3.27 ± 0.23ΔΔ1.28 ± 0.36ΔΔ0.44 ± 0.09ΔΔ
COE-L1.64 ± 0.23Δ2.40 ± 0.471.52 ± 0.37ΔΔ0.32 ± 0.09ΔΔ
COE-H1.35 ± 0.232.35 ± 0.522.17 ± 0.280.23 ± 0.06
ROS1.34 ± 0.532.14 ± 0.902.09 ± 0.45Δ0.27 ± 0.06

Data were presented as mean ± standard deviation (). TG: triglyceride; TC: total cholesterol; HDLC: high-density lipoprotein cholesterol; LDLC: low-density lipoprotein cholesterol. Mice were supplemented with COE at 50 (COE-L) or 200 (COE-H) mg/kg body weight and rosiglitazone at 4 mg/kg body weight (ROS) for 4 weeks. compared to group DM; Δ and ΔΔ compared to group NC.