African Ancestry Gradient Is Associated with Lower Systemic F₂-Isoprostane Levels

Table 2

Relationships between plasma F₂-isoprostanes and study variables.

Continuous/ordinal variables	Spearman correlation coefficient	value
Age	0.148	0.03
BMI	0.189	<0.01
Morbidity	0.437	<0.01
Categorical variables (Kruskal-Wallis test)	F2-isoprostane level mean (SD); (pg/mL)	value
Race
NHW	80.1 (34.9)	<0.001
AA	51.1 (20.1)
NHW	80.1 (34.9)	<0.001
WAI	33.8 (9.0)
AA	51.1 (20.1)	<0.001
WAI	33.8 (9.0)
Sex
Females	59.4 (35.8)	0.43
Males	51.1 (23.2)
Education
College graduate	50.5 (24.8)	0.26
Some college	59.2 (35.2)
HS grads	60.9 (30.1)
Less than HS	53.8 (31.0)
Obesity
Nonobese	51.1 (23.2)	0.04
Obese	69.2 (35.8)
Heart disease
Yes	58.6 (30.1)	<0.01
No	47.0 (24.9)
Endocrine disease
Yes	56.6 (23.9)	0.09
No	50.8 (28.3)
Kidney disease
Yes	82.6 (32.3)	<0.01
No	49.3 (25.9)
Allergy conditions
Yes	67.0 (28.4)	<0.01
No	46.4 (25.6)
Cancer
Yes	79.7 (45.0)	0.07
No	50.3 (26.4)

score summarizes the number of comorbidities.