The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers

<div>SIRT1 and HuR mRNA increase after a PM treatment in human granulosa cell. (a) After 72 h of treatment, human granulosa cells cultured in the presence of 50 <i>μ</i>M PM showed a significant reduction of proliferation. (b) SIRT1 and (c) HuR mRNA expression levels after 50 <i>μ</i>M PM treatment were evaluated by performing a q-RT PCR. RNA18S was used as an endogenous control. Data represent means ± SEM. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers 

Figure 4 | The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers 