Research Article
The Natural Carotenoid Crocetin and the Synthetic Tellurium Compound AS101 Protect the Ovary against Cyclophosphamide by Modulating SIRT1 and Mitochondrial Markers
Figure 5
CPM treatment induces an increase of SIRT1 and HuR. Protein analysis was conducted on ovaries from 8-week-old mice (, per experimental group) removed 12 or 24 hours after a single dose of CPM. Western blots of SIRT1 (a) and HuR (b) and representative images (c). Fold change is represented as a bar graph. Experiments were repeated three times with similar results. One-way ANOVA (), followed by multiple comparison by Holm-Sidak (; ).
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