Differential Alterations of the Mitochondrial Morphology and Respiratory Chain Complexes during Postnatal Development of the Mouse Lung

Figure 6

Transmission electron micrographs of mitochondrial ultrastructure in the ciliated cells, club cells, and alveolar epithelial type II cells (AECII) from the lungs of newborn (NB), P15, and adult (AL) animals. Ultrathin sections of lung samples for routine electron microscopy were contrasted with uranyl acetate and lead citrate prior to analysis by transmission electron microscopy. The left panel (a–f) represents the TEM images of ciliated cells, the middle panel (g–l) represents the club cells, and the right panel (m–r) represents the AECII cells. Higher magnifications of selected areas (b, d, f, h, j, l, n, p, and r). L, lamellar body; N, nucleus; S, secretory granule. Bars: a, c, e, g, i, k, m, o, and q = 0.5 μm and b, d, f, h, j, l, n, p, and r = 0.25 μm.