Pyrrolidine Dithiocarbamate (PDTC) Inhibits DON-Induced Mitochondrial Dysfunction and Apoptosis via the NF-κB/iNOS Pathway

Figure 3

PDTC protects cells from DON-induced iNOS expression. (a) Cells were treated with DON, PDTC, and PDTC pretreatment followed by DON to assess iNOS transcription by qRT-PCR. (b). Cells were treated with DON, DON, PDTC, and PDTC pretreatment followed by DON to assess iNOS expression by western blotting. values < 0.05 are indicated by a single asterisk, . values < 0.01 are indicated by double asterisks, .

(a)

(b)