Pyrrolidine Dithiocarbamate (PDTC) Inhibits DON-Induced Mitochondrial Dysfunction and Apoptosis via the NF-κB/iNOS Pathway

Figure 5

PDTC protects cells from DON-induced apoptosis in GH3 cells. Cells in the control group (a), cells treated with PDTC (b) and DON (c), and cells pretreated with PDTC followed by DON treatment (d) were used to assess the apoptosis rate. Data are shown as means for three separate experiments performed in triplicate.

(a)

(b)

(c)

(d)