Research Article

Chemerin, Inflammatory, and Nitrooxidative Stress Marker Changes Six Months after Sleeve Gastrectomy

Table 1

Comparison of anthropometric and laboratory characteristics between groups.

VariablesControlMorbidly obese value

Age (years)36.38 ± 6.342.15 ± 6.860.05
Weight (kg)57.38 ± 6.74136.85 ± 28.32<0.001
BMI (kg/m2)21.34 ± 2.7348.54 ± 9.27<0.001
TC (mg/dl)150 ± 22.82187.35 ± 43.080.032
HDL-C (mg/dl)40.18 ± 8.7149.66 ± 15.810.135
LDL-C (mg/dl)93.80 ± 19.34112 ± 39.830.242
Triglycerides (mg/dl)80.50 (69.50–89)122 (116–173)0.004
Fasting blood glucose (mg/dl)90.75 ± 7.19104.15 ± 21.060.093
Insulin (μU/ml)6.84 ± 3.6419.28 ± 19.090.215
HOMA-IR1.43 (0.78–2.08)3.31(2.66–5.05)0.008
hsCRP (mg/l)0.26 (0.10–0.48)16.98(11.30–18.30)<0.001
TNF-α (pg/ml)19.52 (12.17–25.65)25.64 (23.21–52.60)0.06
Chemerin (ng/ml)25.13 (21.73–29.95)47.44(26.63–65.73)0.07
NOx (μmol/l)48.51 (44.80–53.74)71.94 (68.46–76.91)<0.001
TOS (μmol H2O2 equiv./l)19.26 (16.33–24.67)93.19 (52.37–117.83)<0.001
TAR (mmol trolox equiv./l)0.62 (0.60–0.63)0.88 (0.63–1.10)0.007
OSI31.39 (26.42–41.48)142.27 (47.72–185.49)0.001

BMI: body mass index; %EBMIL: excess body mass index loss; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment of insulin resistance; hsCRP: high-sensitivity C-reactive protein; TNF-α: tumor necrosis factor alpha: NOx: nitrites/nitrates; TOS: total oxidative status: TAR: total antioxidant response; OSI: oxidative stress index. Mean ± standard deviation or median (interquartile interval: Q1–Q3); Student for independent groups or Mann–Whitney’s test.