Chemerin, Inflammatory, and Nitrooxidative Stress Marker Changes Six Months after Sleeve Gastrectomy
Table 1
Comparison of anthropometric and laboratory characteristics between groups.
Variables
Control
Morbidly obese
value
Age (years)
36.38 ± 6.3
42.15 ± 6.86
0.05
Weight (kg)
57.38 ± 6.74
136.85 ± 28.32
<0.001
BMI (kg/m2)
21.34 ± 2.73
48.54 ± 9.27
<0.001
TC (mg/dl)
150 ± 22.82
187.35 ± 43.08
0.032
HDL-C (mg/dl)
40.18 ± 8.71
49.66 ± 15.81
0.135
LDL-C (mg/dl)
93.80 ± 19.34
112 ± 39.83
0.242
Triglycerides (mg/dl)
80.50 (69.50–89)
122 (116–173)
0.004
Fasting blood glucose (mg/dl)
90.75 ± 7.19
104.15 ± 21.06
0.093
Insulin (μU/ml)
6.84 ± 3.64
19.28 ± 19.09
0.215
HOMA-IR
1.43 (0.78–2.08)
3.31(2.66–5.05)
0.008
hsCRP (mg/l)
0.26 (0.10–0.48)
16.98(11.30–18.30)
<0.001
TNF-α (pg/ml)
19.52 (12.17–25.65)
25.64 (23.21–52.60)
0.06
Chemerin (ng/ml)
25.13 (21.73–29.95)
47.44(26.63–65.73)
0.07
NOx (μmol/l)
48.51 (44.80–53.74)
71.94 (68.46–76.91)
<0.001
TOS (μmol H2O2 equiv./l)
19.26 (16.33–24.67)
93.19 (52.37–117.83)
<0.001
TAR (mmol trolox equiv./l)
0.62 (0.60–0.63)
0.88 (0.63–1.10)
0.007
OSI
31.39 (26.42–41.48)
142.27 (47.72–185.49)
0.001
BMI: body mass index; %EBMIL: excess body mass index loss; TC: total cholesterol; HDL-C: high-density lipoprotein cholesterol; LDL-C: low-density lipoprotein cholesterol; HOMA-IR: homeostasis model assessment of insulin resistance; hsCRP: high-sensitivity C-reactive protein; TNF-α: tumor necrosis factor alpha: NOx: nitrites/nitrates; TOS: total oxidative status: TAR: total antioxidant response; OSI: oxidative stress index. Mean ± standard deviation or median (interquartile interval: Q1–Q3); Student for independent groups or Mann–Whitney’s test.