Lycium europaeum Extract: A New Potential Antioxidant Source against Cisplatin-Induced Liver and Kidney Injuries in Mice
Table 4
Effects of Lycium europaeum and quercetin on serum biochemical parameters of cisplatin-treated mice.
Groups
Kidney function
Liver function
Urea (μmol/L)
Creatinine (μmol/L)
Uric acid (μmol/L)
BUN (mmol/L)
AST (U/L)
ALT (U/L)
LDH (U/L)
Control
35.51 ± 1.57
52.29 ± 0.80
20.39 ± 0.87
4.63 ± 0.22
63.61 ± 1.71
60.12 ± 1.57
21.68 ± 0.98
LEM
35.84 ± 4.51
51.06 ± 1.05
19.37 ± 0.78
4.39 ± 0.64
60.29 ± 2.22
59.28 ± 1.33
20.82 ± 0.37
Cisplatin
68.01 ± 2.03
96.01 ± 1.80
30.58 ± 0.25
8.99 ± 0.14
111.20 ± 6.47
97.49 ± 2.14
56.36 ± 1.67
LEM + cisplatin
39.02 ± 0.65
71.98 ± 1.86
25.36 ± 0.90
5.66 ± 0.35
71.05 ± 1.93
70.43 ± 0.93
28.02 ± 1.66
Quercetin + cisplatin
40.56 ± 4.34
67.68 ± 1.61
22.16 ± 0.96
5.39 ± 0.24
65.3 ± 0.86
69.01 ± 2.20
22.92 ± 1.70
Values represent mean ± SEM from three independent experiments, mice per group. Significant difference at and significant difference at : the cisplatin group versus the control group. Significant difference at and significant difference at : the LEM + cisplatin and quercetin + cisplatin groups versus the cisplatin group.
