Honokiol Protects against Anti-<i>β</i>1-Adrenergic Receptor Autoantibody-Induced Myocardial Dysfunction via Activation of Autophagy

<div>Honokiol activated the AMPK/ULK1 pathway. (a) Representative Western blot images of p-AMPK (Thr172), AMPK, p-ULK1 (Ser555), and ULK1 in cardiac tissue lysates from each group. (b) Quantification and comparison of p-AMPK and AMPK band values from (a). (c) Quantification and comparison of p-ULK1 and ULK1 band values from (a). The phosphorylation of AMPK and ULK1 were inhibited by <i>β</i>1-AAB and activated by HNK. 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HNK: honokiol.</div>

Oxidative Medicine and Cellular Longevity

fig7

Figure 7

Figure 7: Honokiol Protects against Anti-<i>β</i>1-Adrenergic Receptor Autoantibody-Induced Myocardial Dysfunction via Activation of Autophagy 

Oxidative Medicine and Cellular Longevity

Honokiol Protects against Anti-β1-Adrenergic Receptor Autoantibody-Induced Myocardial Dysfunction via Activation of Autophagy

Figure 7