GRP78 Promotes Neural Stem Cell Antiapoptosis and Survival in Response to Oxygen-Glucose Deprivation (OGD)/Reoxygenation through PI3K/Akt, ERK1/2, and NF-<i>κ</i>B/p65 Pathways

<div>Role for GRP78 in OGD/reoxygenation-induced PI3K/Akt and ERK1/2 activations. (a) Protein expression of GRP78 in GRP78 knocked-down NSCs with OGD/reoxygenation induction, for siRNA transfecting efficiency determination. (b–d) Abolished phosphorylation of PI3K, Akt, and ERK1/2 by OGD+R induction in GRP78 knocked-down NSCs. 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Oxidative Medicine and Cellular Longevity

fig3

Figure 3

Figure 3: GRP78 Promotes Neural Stem Cell Antiapoptosis and Survival in Response to Oxygen-Glucose Deprivation (OGD)/Reoxygenation through PI3K/Akt, ERK1/2, and NF-<i>κ</i>B/p65 Pathways 

Figure 3 | GRP78 Promotes Neural Stem Cell Antiapoptosis and Survival in Response to Oxygen-Glucose Deprivation (OGD)/Reoxygenation through PI3K/Akt, ERK1/2, and NF-κB/p65 Pathways 