Gengnianchun Extends the Lifespan of Caenorhabditis elegans via the Insulin/IGF-1 Signalling Pathway

Figure 1

GNC treatment extended the lifespan and enhanced resistance to heat stress and oxidative stress in C. elegans N2. (a) The lifespan of C. elegans N2 at 20°C. (b) Survival percentage of N2 nematodes subjected to acute heat stress. (c) Survival percentage of N2 nematodes subjected to H₂O₂-induced oxidative stress. (d) Survival percentage of N2 nematodes subjected to paraquat-induced oxidative stress. (b–d) After treatment with 3.94 mg/mL GNC for 48 h, nematodes were dipped into 16 mM H₂O₂ for 4 h or 5 mM paraquat for 9 consecutive days or moved into a 35°C incubator, and then, the surviving worms were counted. The data are displayed as the mean ± SEM. ; .

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