Research Article
Remote Ischemic Preconditioning Ameliorates Acute Kidney Injury due to Contrast Exposure in Rats through Augmented O-GlcNAcylation
Figure 5
Alloxan decreases protein O-GlcNAcylation and blunts the renoprotection of RIPC in CI-AKI. (a, b) The immunoblots and the quantitation of the global renal O-GlcNAcylation levels from rats 24 h after iohexol treatment, (c) detecting UDP-GlcNAc concentrations in renal tissues and analyzing serum and urine biomarkers. Serum (d) and urinary (e) NGAL; SCr (f). (g, h) Photos of renal tubular injury. Scale bars represent 100 μm (original magnification, ×200). , compared with the RIPC + CM group; compared with the sham + CM group; .
(a) |
(b) |
(c) |
(d) |
(e) |
(f) |
(g) |
(h) |